Oral health
ProDentim
A soft chewable oral probiotic for adults who want to support healthy teeth and gums alongside brushing and flossing. ProDentim delivers 3.5 billion CFU of five probiotic strains, including the BLIS K-12 and BLIS M-18 strains studied for oral and throat health, in a mint-flavored tablet that melts in the mouth.†
- Format
- Soft chewable tablet, one per day, allowed to dissolve in the mouth
- For
- Adults (18+)
- Made in
- USA, GMP-certified & FDA-registered facility; non-GMO, gluten-free (manufacturer's claims)
- Price
- US$49 to $79 per bottle depending on bundle (2, 3 or 6 bottles); 3- and 6-bottle bundles ship free
- Guarantee
- 60-day money-back guarantee (return shipping at customer's expense)
- Our review
- buyprodentimsupplement.com
- Where to buy
- Through the official vendor link on our review site. Three Whole Health does not sell this product.
What is in ProDentim
Most probiotics are designed to survive the stomach and work in the gut. ProDentim is different: the tablet dissolves in the mouth so the strains come into contact with the teeth, gums and throat first.
| Ingredient | Why it is included |
|---|---|
| Probiotic blend, 3.5 billion CFU | Lactobacillus paracasei, Lactobacillus reuteri, Bifidobacterium lactis BL-04, Streptococcus salivarius BLIS K-12 and BLIS M-18. The BLIS strains were isolated from the mouths of people with naturally healthy oral flora and are among the most studied oral probiotics. |
| Inulin (chicory root), 100 mg | A prebiotic fiber that serves as food for beneficial bacteria. |
| Malic acid | A fruit acid traditionally used to support saliva flow. |
| Tricalcium phosphate | A calcium source associated with tooth enamel. |
| Peppermint and spearmint | Natural flavor and fresh breath. |
Why an oral probiotic
The mouth has its own microbiome, and an imbalance in it is linked to plaque, bad breath and gum irritation. Research on S. salivarius K-12 and M-18 suggests these strains can crowd out less helpful bacteria and support gum and throat health. ProDentim is meant to add to, not replace, a routine of twice-daily brushing, flossing and regular dental check-ups.
How to use
- Chew or let one tablet dissolve slowly in the mouth each morning.
- Wait a few minutes before eating or drinking so the strains stay in contact with the gums.
- Allow 4 to 8 weeks of consistent use before judging results.
Talk to your clinician or dentist first if you are immunocompromised, pregnant or nursing, recovering from major surgery, or have a diagnosed gum disease. Probiotics are not a treatment for gingivitis, periodontitis or tooth decay.
Quality and manufacturing

The manufacturer states that ProDentim is produced in the United States in a GMP-certified, FDA-registered facility. We treat manufacturing statements as vendor claims and note on our review site which ones are documented. See How We Work for how we assess them.
Frequently asked questions
Can ProDentim replace brushing?
No. It is a daily supplement to support a balanced oral microbiome. Keep brushing, flossing and seeing your dentist.
Does it need refrigeration?
No. Store the bottle in a cool, dry place away from direct sunlight.

Where can I buy ProDentim?
ProDentim is sold only through the manufacturer's official website, with orders processed by ClickBank. Our review site, buyprodentimsupplement.com, links to it. Three Whole Health does not sell ProDentim and may earn a commission on purchases made through that link.
† These statements have not been evaluated by the Food and Drug Administration. The products reviewed on this site are not intended to diagnose, treat, cure, or prevent any disease.